Follow Us On Twitter
Home | Appointments | About The Center
Johns Hopkins Arthritis CenterJohns Hopkins Medicine
  • Arthritis Info
  • Patient Resources
  • Physician Resources
  • Arthritis News
  • Arthritis Research
  • Ask The Expert
ACR 2006 Highlights from Johns Hopkins University
Home > Physician Corner > Physician Education > ACR 2007 Highlights > RA Safety

Rheumatoid Arthritis Treatment: Safety

Is TNF Inhibitor Use Associated with Adverse Maternal-Fetal Outcomes?

Although TNF inhibitor use during pregnancy does not appear to lead to adverse outcomes in animal models, human data are limited and current recommendation mandate discontinuation during pregnancy, delivery, and breast feeding.  Two abstracts presented as podium presentations addressed the issue of fetal outcomes associated with TNF inhibitor use, with seemingly discordant conclusions.

  • Abstract 667: A Safety Assessment of TNF Antagonists during Pregnancy: A Review of the FDA Database
  • Abstract 730: Pregnancy Outcome after Exposure to Biologics: Results from the German Biologics Register RABBIT

Other Safety Abstracts

  • Abstract 1343: Rheumatoid Arthritis, Interstitial Lung Disease, Mortality, and Anti-TNF Therapy: Results from the BSR Biologics Register (BSRBR)
  • Abstract 1344: Are Cancers Occurring in RA Patients Treated with TNF Antagonists Particularly Aggressive?

AddThis Social Bookmark Button

All information contained within the Johns Hopkins Arthritis Center website is intended for educational purposes only. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. Consumers should never disregard medical advice or delay in seeking it because of something they may have read on this website.

  • ACR 2007 Highlights
  • Rheumatoid Arthritis
  • Clinical Aspects
  • Safety
  • TNF Antagonists
  • Treatment
  • Spondyloarthropathies
  • Pediatric Rheumatology
  • Osteoarthritis
  • Gout
  • Lupus
  • Myositis
  • Osteoporosis
  • Scleroderma
  • Sjogrens Syndrome
  • Vasculitis
  • Basic Science
  • Epidemiology
  • ACR 2006 Highlights
  • CME Activities
  • ACR Daily Highlights
  • ACR Daily Podcasts
  • ACR Skyscape PDA Highlights
  • ACR Toolkit
  • CME Activity Home

Signup For Our Email Newsletter

Sitemap | Copyright |Privacy Policy | RSS |Contact Us | Hopkins Rheumatology