Abstract 298 Relationships between spinal OA, vertebral fracture and bone mass. The Rancho Bernardo Study.
Grigorian M, Schneider DL, Fem Bo et al.

This study of 560 adults age 55-92 years (218 men, 342 women) demonstrated that radiographically confirmed spinal OA was associated at baseline with higher spinal BMD and less spinal bone loss over time, and also a lower incidence of vertebral fractures in women.

Editorial Comments: These results further support the inverse relationship between OA and OP.

Abstract 1571 Rapid and Sustained Anti-fracture Efficacy of Strontium Ranelate in Post-Menopausal Osteoporosis.
Reginster JY, Sawicki A, Devogelaer JP, et al.

This was a study to examine the efficacy of strontium (SR) on bone metabolism given its known ability to reduce bone resorption while also increasing bone formation. This double-blinded, RCT enrolled 1649 women across 72 centers and 12 countries.

Results: A significant reduction in the number and proportion of new vertebral fractures was observed in the SR group after 1 year of treatment(p < 0.001; RR 0.47) and also after 3 years (RR=0.49). SR was well tolerated without significant adverse effects

Editorial Comments: Vitamin D and calcium were also taken by all subjects.

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