What do you think of ELISA testing for ANA as opposed to IFA testing?

What do you think of ELISA testing for ANA as opposed to IFA testing?

Answer:  For those not familiar, many if not all of the larger commercial labs have switched theier ANA testing to ELISA systems.  In my expereince there is a difference between the older IFA (immunofluoresce) testing and ELISA-- some patients are positive only on one of the assays.  I could see how ELISA might be more reproducible, but I would still favor IFA.  The future will likely be all ELISA.

Last update: 01:43 AM Friday, May 25, 2007

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Author:

Alan Matsumoto, M.D.

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