antibiotics and methatrexate

Question  I have been on methatrexate for 5 weeks. I have LLL pneumonia and am taking leavaquin po daily. Is there a contraindication/ Does the methatrexate inhibit the antibiotic or vice-versa? thanks
 
Answer  There should not be an issue with Levaquin. Bactrim, (trimethoprim Sulfa) should be used cautiously with methotrerxate because it can increase the toxicity of methotrexate.

Last update: 05:57 PM Thursday, April 12, 2007

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Alan Matsumoto, M.D.

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