Vitamin D deficieincy

Great question.  There is some evidence that low Vitamin D levels can be associated with fairly nondescript muscle and joint pain. Remember that kids with severe vitamin D deficiency are the ones who develop rickets !!

 In patients with inflammatory arthritis like rheumatoid arthritis, there are also some data suggesting that low vitamin D levels make the joints more inflamed, but this remains to be proven by a clinical trial (we are doing one here at Hopkins).