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How long for Orencia
We have safety data extending out several years with Orencia (abatacept). Many patients will continue to see improvments on this medication over time. No significant new or unexpected side effects have ......

Allergic reactions and serious infections from DMARDS
? Ive been on 15mg of MTX for 2 years but need more help. My Rhematologist has suggested anti TNF. Is it true that there are more side effects in terms ......

Efficacy of Plaquenil versus a generic Hydroxychloroquine formulation
The active ingredient of brand name Plaquenil and generic hydroxychloroquine are the same.  In the United States, the manufacture of prescription drugs is highly regulated and the manufacturer is required, by ......

Is Enbrel made from fetal tissue?
Enbrel (etanercept) is not made of fetuses. However, the protein is entirely human and produced by recombinant DNA technology. Please see our section on RA Treatment for complete details on Enbrel and its ......

Concerned with increasing Methotrexate
  I have arthritis and am being treating with methotraxate and enbrel which was working superbly until recently when I started having strange sensations in my head and experienced extreme fatigue ......

Efficacy of Sulfasalazine?
  Hi, I'm 19 and I was diagnosed with RA in November last year. Before I was diagnosed I was put on 20mg prednisolone, etoricoxib 90mg and co-codemol. Once diagnosed I ......

Combination of Arava and Methotrexate safe?
  My wife is in India and currently under the treatment of a rhematologist there. she is taking 7.5 mg of methotrexate every week. She is due for a follow up ......

Mixing other medications with Enbrel, such as cough medicine.
  Can you take cough medicine or other remedies from over the counter, if you are taking enbrel injections (anti-tnf)?     This should not be a problem to take cough ......

Can Rheumatoid Arthritis affect the eyes?
  My mother is 62 y.o and dx'd with RA with nodes on her fingers, and had a previous MRI noting disc dissecation in her L spine. Recently, she woke up ......

Outcomes of Arava vs Humira for RA
  Please compare the outcomes of Arava vs Humira for RA. I am 51, have been on both in the past and need to choose between them.     I can ......

Pregnancy and Methotrexate
  I was taking methotrexate 8 pills 1 x a week at 2.5 mg.  I began last August and stopped this past March.  I want to get pregnant but I have ......

Slow healing skin issues while taking Enbrel?
  I have been regularly taking 50 mg. shots of enbrel a week for the past seven months.  It has worked wonders.  However, over the past six weeks I have noticed ......

Humira and Lupron Interactions?
  I am currently taking humira for AS but I also have endometriosis which I was taking the lupron injections for is there any drug interactions if I took both   ......

Possible resistance to Remicade?
  I have lupus and sjogren syndrome started on remicade and now are going every month. It was working  but last month they increased my dose and this has made me ......

Methotrexate and Side Effects
  My questions are regarding a 48 yr. old male patient that was diagnosed with rheumatoid on Feb. 6, 2004 (with a rheumatoidfactor of 300+).His current medications are:-Prednisone 5mg daily (began ......

Spondyloarthritis treatment
  I have spondyloarthritis and need the latest treatment recommendtions. At the present time, the pain is in the left neck and 24 hour headaches.     Unfortunately, our section on ......

Will delaying treatment of RA cause deformity?
  I am a 34yr old dental hygienist who has been having joint pain and stiffness in both wrists, hand/finger joints and toe joints for about 4 mos. Sometimes the pain ......

RA and Methotrexate
  Approximately six months ago I was diagnosed with RA. In March I had my first appointment with a Rheumatologist who has done an excellent job of explaining RA to me ......

pamidronate in AS
  I have had As for 6 years and recently have been in terrible pain after a car accident jerked my neck and back which has aggravated condition further. I have ......

Will Methotrexate and Prednisone cure Rheumatoid Arthritis?
  will methotrexate and Prednisone cure Rheumatoid Arthritis.     None of the available therapies "cure" rheumatoid arthritis. The medications help the symptoms and in the case of drugs such as ......

Use of ETANERCEPT with AS
  I have been recommended for the above drug and would like to know if it has recorded any side effects with the patients that have been prescribed this course of ......

Stomach problems with Plaquenil
  I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature (off and on for a year), joint pain and ......

Effects and use of methotrexate
  I have RA which, until recently has been well controlled with sulphasalzine, Bextra and prednisone when needed. Most recent x-rays show significant erosion in my hands. My Rhumatologist would like ......

Psoriatic Arthritis
  I am a 70 year old female with a history of minor guttate typepsoriasis. Father had it and fingers were slightly clubby looking. I developed around 55 years. Last year ......

Taking remicade
  For three years I took Embrel with much sucess, but it is too expensive for me to pay. My doctor put me on remicade and my insurance will pay the ......

Dealing with the pain of RA /Progression of RA
  I have had RA for 8 years, I continue to try to "get through the pain" as I don't like to take alot of medications. Is this hurting me more ......

Endometriosis and Enbrel
  If someone has endometriosis, is it safe to take enbrel - given the infection side effect of enbrel?     Endometriosis is not an infection but is due to uterine ......

RA and Endometriosis
  I have RA and was recented diagnosed with endometriosis. The medications used for both seem to conflict. Is it safe to take methotrexate and lupron together. What risks can Lupron ......

When will I get some relief from my Rheumatoid Arthritis
  I have been having pains and swelling in my joints since may. Saw my family doctor and she diagnosed it as arthritis but it did not respond to anything she ......

Skin reactions...
  Since my RA diagnosis (2/6/2004), I have been treated with prednisone (10mg/day), minocycline (200mg/day), methotrexate (for 90 days, discontinued for intolerance), Arava for 5 weeks (discontinued for intestinal and bowel ......

Remicade use for Adult Onset Still's Disease
  I am a 36 yr old female w/Still's Disease, diagnosed 1995 at the University of Kentucky. I have had several flares in my lifetime and been on different meds each ......

RA - when/why are x-rays ordered
  I am a 45 year old female who was diagnosed with RA 8 years ago. My rheumatologist has never ordered x-rays and I am becoming concerned since my elbow and ......

Side effects of Methotrexate
  I was on Methotrexate for over 6 months wihout much relief and asked for differant drugs. I had to have a ct scan and pulmonary nodules were found in the ......

Enbrel and uveitis
  My son has had AS for 12 years and has been on Enbrel for approx one year with excellent results. However, he recently had a bout of uveitis in his ......

Effect of Humira and Methotrexate on Lungs
  I have been taking Methotrexate 20mg for several years. In 2004, Humira was added to my treatment. Now 1 year later, I have a lesion in my left lung, (soon ......

methotrexate and alcohol
  I have recently started methatrexate 7.5mg a week (4 weeks ago).I usually have a glass of wine or two with dinner and my husband and I go out on a ......

Pneumonia shot??
  I am 43 and was diagnosed with RA three years ago. I am currently on humira and MTX and having good results. I do have a history of pleurisy and ......

Dermatomyositis
  My daughter had been treated with Azathioprine for Dematomyositis. She is 18years old now & pregnant. Is she or the baby in danger from Azathioprine?     You need to ......

Re: enbrel 25 mg
  has anyone developed cancer from taking enbrel? it so, what kinds?     The issue of cancer and the TNF inhibitors (Enbrel, Humira, Remicade) is being watched very carefully. Although ......

Surgery and Enbrel
  I have undergone two fusion attempts for C1-C2 instability which have both failed. I am about to undergo a third attempt with screws and a cable instead of just wire. ......

Enbrel in a 78 year old woman/ Is it worth risk?
  I am a pediatrician who is not very familiar with Enbrel. My mother is 78 years old and has been taking NSAIDS for RA which she has had for over ......

Remicade and surgery
  I am on remicade and methotrexate and need a total knee replacement are there any information on this, and should I stop the remicade and methotrexate before i have the ......

Patient with RA on Remicade and in need of a knee transplant
  I am 57 and I have RA.  I am currently on the drugs remicade and methotrexate.. I need a total knee replacement I wanted to know how well other patients ......

Moving from Enbrel to Humira
  I have AS and Enbrel worked brilliantly for one year. It has suddenly stopped being effective. Prior to being on Enbrel I was on Remicade, that too, after a year ......

long term prednisone vs methotrexate for pmr
  I was first diagnosed w/ pmr in 2001..originally on prednisone then added methotrexate to taper off prednisone... I was in remission for about 1 yr only using otc meds... In ......

Leflunomide
  Dear Sir,Does Leflunomide increase the suceptibility to infection to tuberculosis? Should it be used in persons having chronic infections like Tuberculosis?Thanks     In the RA patient population, we have ......

methotrexate toxicity
  I take a relatively low dosage of methotrexate once a week. I feel weak, tired and slightly sick for a day and a half after each dose. I also take ......

Enbrel plus methotrexate - family planning
  I am a male on Enbrel with Methotrexate, is it safe to start to have children?     Methotrexate can affect DNA replication and thus there is potential to cause ......

methotrexate during pregnancy
  If you get pregnant while taking methotreate, will I abort it?     A review article by M.E. Lloyd et al (QJ Med 1999; 92:551-563) titled "The effects of methotrexate ......

Remicade and Toxicity
  I have Ankylosing Spondalitis and have had 8 Remicaid infusions so far, at 8 week intervals.The first 6 treatments left me feeling fantastic within a day of the treatment.The last ......

Availability of injectable Methotrexate?
  Why did injectable MTX suddenly become unavailable a few months ago? Will it be available again? I have lived the RA adventure for 41 years now (diagnosed at age 17), ......

Methotrexate for Rheumatoid Arthritis
  Dear sir,I want to know that what should be the minimum level of haemoglobin to start the methotrexate ?     There is no minimum level. The critical question is ......

Blood Pheresis as an alternative RA treatmemnt
  After recent consults with the Mayo Clinic, Yale University and Harvard/Brigham Womens Hospital -- it has been suggested that I engage in blood pheresis (Prosorba Column) as an alternative to ......

TNF meds causing CNS disorder
  My question is regarding TNF medications. Last March while on remicade, I had sever headaches for a month followed by lighheadedness and blurry vision. Went immediately to my optomalogist and ......

Methotrexate and future pregnancy
  I am 32 years old and have had one child a year ago. I recently was diagnosed with seronegative arthritis. I will be starting methotrexate next week. My husband and ......

Enbrel and seizures
  I was on Enbrel for about a year and a half. Soon after beginning the medicine, I began to have difficulty with my speech, mainly with talking in past tense. ......

Humira/Remicade For Chronic Low Back Pain?
  Hello Doctor, I am a 50 yr. old WM, who has chronic lumbosacral radiculopathy from failed BAK cage assisted fusion surgery in 1998.High dose opioid/NSAID therapy is absolutely essential, but ......

Tamoxifen and Methotrexate
  If you had a patient on Tamoxifen to prevent a recurrance of breast cancer would you be concerned about the patient also taking low doses of Methotrexate for RA- in ......

How long to be on MTX before tapering off?
  My 7-yr old son is on 17.5mg MTX sub-cut injections once a week.He has been inflammation free for 6 months.There seems to be a differing opinions among some of my ......

Arava and Methatrexate
  I take arava and methatrexate for RA and muscle disease. I've been on these medications and then some for one year. My blood tests have been coming back okay since ......

Storing of Remicade
  I understand that Vials of Remicade should be refrigerated.What if I took a vial out of refrigeration and left it say at roomtemperature for say 12 to 14 hours. Would ......

Methotrexate and vertigo
  Dear sir,I am taking Methotrexate for Rheumatoid arthritis, this is the second week . I started with 10 now 15 mg but Iam feeling dizzyIs this a side effect of ......

Methotrexate and pregnancy
  I am a male with AS on Enbrel and Methotrexate. My doctor has told me that in the event of trying for a family, I would only have to come ......

Having Hepatitis C and Rheumatoid Arthritis
  My family doctor says I cannot work anymore because of the Hepatits C and Rheumatoid Arthritis. I can hardly move,my whole body aches all the time. My family doctor says ......

Effects of Methotrexate treatment on Kidney
  I have been on weekly treatment of methotrexate injection over the past four years. My age is 45, and I have been diagnosed with RA since my age of 26.Are ......

Remicade infusions for severe polymyalgia
  Have there been any studies done in the use of Remicade infusions for severe polymyalgia? My mom has the disease and cannot take prednisone due to side effects. She has ......

Side Effects of Planquil
  What are the side effects of Plaquenil?     The main concern, although extremely rare is ocular (eye) problems-- usually loss of visual fields (lack of vision in certain areas ......

Effect of Humira and Methotrexate on Lungs
  I have been taking Methotrexate 20mg for several years. In 2004, Humira was added to my treatment. Now 1 year later, I have a lesion in my left lung, (soon ......

Irregular response to Remicade
  It has been over one year that I have had infusions of remicade. February 23, 2005 treatment was the most successful. I felt great for the entire month.The months before ......

Neurological Concerns With Humira
  Could extended use of Humira cause TIA's, strokes and/or short term disorientation?     To my knowledge, what you describe has not been reported. However, there have been rare reports ......

Arava and bleeding
  Patient diagnosed with multiple small bowel telangectasia. Meds being taken are coumadin 4mg/5mg alternating days, lipitor 40mg/da, methotrexate 10mg/wk, Toprol XL 50mg/day. Arava discontinued in March of 05. Is there ......

antibotic therpy for RA
  I'll try to make this short. I am 52 and RA for also 10 years. Had to retire from nursing because of this. Also have fibromyalgia and asthma.I have tried ......

Whats next, Humira??
  I was diagnosed with RA in 2002. I am receving remicade at 5mg every 4 weeks, & methotrexate 15mg weekly. My first 2 remicade treatments, I had reactions where it ......

Enbrel--long term effects on children
  My daughter is 13 years old and has been taking Enbrel for the tx of JRA (she was diagnosed at age 2 years) for approx. 9 months with good results. ......

Enbrel or Humira without methotrexate
  Varied doses of methotrexate, plus hydroxychloroquine, which I stopped taking because it made me dizzy, have not completely worked. My doctor is now considering putting me on Enbrel or Humira ......

Enbrel Vs. Remicade
  I recently moved to Israel, and am having difficulty in getting my Enbrel prescription continued here. They just recently approved Enbrel for Psoriatic arthritis, but they want me to try ......

Humira once per week
  I was diagnosed with RA last year. I took Enbrel for about 4 months and experienced a significant reduction in RA symptoms. My rheumatologist suggested that I take Methotrexate with ......

Rheumatoid Arthritis
  I have Rheumatoid Arthritis. I was wondering what is the normal drug treatments for RA. Should they be tried in any order. Like starting with NSAID then Steroids then drugs ......

Is Enbrel an OK Treatment for Scleroderma
  My rheumathologist, has told me that he will be using Embrel to treat my scleroderma/ mixed connective tissue illness. What is your advise on this? I am on metotrexate and ......

Can Methotreate cause nerve pain/neuropathy?
  I have been taking methotreate (10 mg a week) for 13 years for psoriatic arthritis. I have developed very servere nerve pain in my feet and ankles. The EMG and ......

persistant cough
  I have had a really bad cough for the last 2 months . I have had 2 rounds of antibiotic but I am also on MTX and plaquenil . Can ......

Rheumatoid & Methotrexate
  I have recently stopped my methotrexate, and I feel fine. It has been 2 months now, I am wondering exactly what does Methotrexate do for rheumatoid?     Methotrexate reduces ......

Methatrexate and Alcohol
  I'm a 33 year old male with psoratic athritis i take 15mg of methatrexate weekly.It really has helped my joints the only thing is that i like the odd beer.Some ......

Psoriatic Arthritis long term prognosis w/o Tx
  I am a 49 year old woman, Dx'd with psoriatic arthritis which had gone undiagnoised and untreated for probably 5 years or more, which is in the spine, Just three ......

Oral Medications for RA treatment
  I have recently been diagnosed with RA after being treated for Polymyalgia for at least a year.My doctor has me on 7.5mg Methotrexate weekly, Plaquenil(GEQ)200mg twice daily,Prednisone 2mg daily and ......

Remicade and wound healing
  Does Remicade retard wound healing. Should Remicade be discontinued prior to elective open heart surgery??     Remicade should not cause problems with wound healing. The concern with Remicade and ......

Arava Liver Failure, Update Please
  In 2002 arava was being petitioned to be taken off the market because of severe liver problems. Have there been new studies about it's safety? My rheumatologist started me on ......

Increase methrotexate or add a new drug?
  My sister is 37 years old and she was diagnosed with RA 2 years ago.  She was on 20Mg IV Methotrexate, still with mild symptoms.  Her new doctor decreased the dosage ......

Weekly Humira Injections
  I have been on Humira for 5 months, & initially had a a great response to the first two injections. Since then it doesn't seem to have been as effective. ......

Biologics - Injectables or IV - Patient Consensus?
  I am sero negative RA (Still's Disease). Because of initially diverse symptoms,diagnosis took a long time. When referred to a rheumatologist, she worked it up pretty quickly. Anyway, have been ......

Drugs,Alcohol, and Arthritis
  My mother-in-law was diagnosed with RA a few years ago. For a while she was self-medicating with illegal substances and alcohol and now her RA is so bad that she ......

Subcutaneous Injection
  What is the maximum amount of medication which can be given Subcutaneous?     There is no right answer. It depends on a variety of factors including but not limited ......

Side effects of the drug, Arava
  The information I have gathered about the scary side effects of Arava is not on your site. Are you behind the knowledge curve or is it untrue that there have ......

When to start DMARDS?
  If you have joint stiffness and pain that is pretty limiting but only marginal chemistry profiles (elevated ESR-40 for male, slightly positive RF) should DMARDS be started or should there ......

Should I Start Methotrexate?
  45 year old male -- I've had joint pain and muscle pain /weakness for the last year. The rheumatologist has vacilated on the diagnosis going from suspecting ankylosing spondylitis, MS ......

Methotrexate
  I take 12.5mg of methotrexate per week for rheumatoid arthritis. I also take 1mg of folic acid every day except on the day I take the methotrexate and the day ......

Failure of Anti TNF Drugs for RA
  Over the last year, I have tried all 3 available Anti TNF drugs. I was on Embrel for 6 months, tried Remicade, but had a reaction& had to stop. I ......

RA and Prednisone
  This is my third time trying to tapper off the Prednisone and this time I am also on Methotrexate. I am reducing the Prednisone and increasing the Methotrexate at the ......

Moving from Enbrel to Humira
  I have been on Enbrel for about 10 months for RA. It has helped a lot, but I still have some stiffness. My Dr. thinks I should move to Humira ......

Pulmonary Fibrosis and Arava
  I have Pulmonary Fibrosis and have recently been diagnosed as also having Rheumatoid Arthritis.I was put on Arava by the Rheumatologist, but on looking at the information on the web ......

Increasing Methotrexate
  I am increasing my Methotrexate and the more I take the more side effects I get. I am now at 15mg per week. I have noticed my hair is falling ......

Enbrel, Preganacy and Adult Onset Still's Disease
  I am 31 years old and have been taking Enbrel for a couple of years for Adult Onset Still's Disease. I disconintued the medication about 4 weeks ago when I ......

is it possible to gain weight on methotrexate??
  I am being treated for systemic Lupus--I have been taking Methotrexate 2.5mg (10 pills 1x a week) for the past 7 months--my weight has some how crept up at least ......

long term prednisone vs methotrexate for GCA
  Have any clinical trials been done done for GCA using low dose Prednisone alone without Methotrexate? I do not want the side effects of Methotrexate and am able to do ......

Methorexate and side effects
  I am taking Methotrexate for RA. I read that there is a small risk of it causing cancer. Can you tell me what type of cancer it might cause. I ......

Rheumatoid Arthritis
  I am on MTX, Prednisone and NSAID. I am anemic, RA and Carpal Tunnel Syndrome. Ohter wise healthy. I hardly ever get a cold or the flu. This is the ......

recently dxed with RA
  HiI was diagnosed with RA last week by a rheumatologist. My internist had referred me due to 3 months of joint pain. I also have multiple sclerosis. The dr. said ......

Treatment of RA plus Sjogrens Syndrome
  I have newly diagnosed RA with high RF and Citrulline antibodies. My Sjogrens Disease ( 8 yrs duration- dry eyes, dry sensitive skin and mucous membranes, peripheral neuropathy ) is ......

Side effects of Methotrexate
  since I increased my Methotrexate from 12.5mg to 15mg then to 20mg per week I got a rash on my wrist and the other hand has no rash but is ......

Remicade Treatment
  I need to ask a question concerning the Remicade treatment for Rheumatoid Arthritis. My sister is trying the Remicade for the second go round. The first time see only made ......

Effectiveness of increased Methotrexate
  For the past 8 years I have been on a weekly dose of 17.5mg of oral Methotrexate and 500mg of Plaquenil( the dose of plaquenil was reduced after 2 years ......

Moving from Enbrel to Humira
  Would there be any reason to be on both Remicade and Humira, at the same time?     There is no rationale for using both together, although I have to ......

NSAID and injecting Methotrexateto control flare
  Thank you for your response to my earlier question, "Effectiveness of increased Methotrexate ".This is a follow up question .The flare ups that I experience are not very severe, in ......

Can I continue my medication while pregnant?
  Hi, Iam planning on getting pregnant. Currently I take 5mg prednisone daily, 25 mg enbrel twice a week, and 15mg Mobic daily. When i do find out that Iam pregnant ......

Radiologist & Rheumatologist disagree
  I received an R.A. diagnosis 2 years ago. X-rays of the hands and feet taken at that time showed no erosions. I have been taking 17.5/mg. of methotrexate since that ......

Cough, a side effect?
  I am on Methotrexate, Arthrotec, and Coversyl(ACE inhibator for high blood pressure) Recently I have developed a dry non-productive cough. Could the cough be from the Methotrexate, RA itself, Coversyl, ......

RA and Drugs
  I didn't notice answers to this, so i wanted to check with you.I have a few questions I hope you can answer that new RA people also might need to ......

Orencia for RA
  I understand this has just been approved by the FDA for RA. Just wondering if you have prescribed it yet and if so how have your patients done? Also, does ......

Methotrexate and Heart Disease
  Does taking methotrexate increase the risk of developing heart disease? If it interfers with folic acid will a person's homocystein levels be affected adversely?Thank you.     I am not ......

How Soon Is It Safe To Get Pregnant After Stopping Enbrel?
  I have been on enbrel for three months my artthritis is well-controlled but I want to get pregnant , question is how soon can I get pregnant after I discontinue enbrel??? ......

MTX vs Plaquenil
  Hello,I hope you can help me make a difficult decision.I am currently on the 4th NSAID to try and treat inflammation of my joints. My doctor said he thinks we ......

Severe itching on Leflunomide
  After being on Leflunomide for about 3 months, I developed a very severe itching all over my trunk - front and back. I have scratched so much, my skin is ......

TNF Blockers
  I am reading about TNF blockers such as Humira, Enbrel, Remicade and others. I have crohns and was just wondering what the difference is in the different types of TNF ......

Methotrexate and Memory Loss
  I am 25 years old and had been on methatrexate since September 2004 and have just been taken off it(January 2006). Over the last year I had noticed that I ......

Methotrexate and effect time
  I am a member of an online chat forum and a conversation came up recently.Someone stated that when you take the weekly dose of metho, that it wears out of ......

Combining biologics to fight flares
  I have advanced psoriatic spondylitis. Enbrel has kept it under control for the past three years but I still have debilitating flares a few times a year. I can't take ......

remicade and rituximab
  Do you have any experience with using these drugs simultaneously?What happened with the length of time of B cell depletion? CD4 count? Infections? Thanks.     I have no direct ......

Biologic agent at 77 ?
  I am 77-years-old and was diagnosed with RA 7 months ago in August. I was treated with medrol alone for 5 months. (8 mg down to 6 mg). Every time ......

Enbrel and missed period
  Can enbrel cause you to miss periods?     No. Other causes of missed menstral periods should be investigated....

RA and Enbrel use
  I have used Enbrel for over a year. The injection sight went away but now is back along with thick patches of red itchy skin on my arms. Can stress ......

RA Pain Management
  I have RA, Carpal Tunnel Syndrome, Anemic and high blood pressure. I am taking Arthrotec, MTX, Prednisone, Coversyl, and Tiazac XC. I am waiting to see a Rheumatologist for biological ......

Humira/Methotrexate combination-alternatives
  I have behcets disease which affects my joints, digestive system , skin and eyes, I have tried azothiaprin but was found to have a gene that means I was unable ......

Aviva as rheumatoid arthritis medicine
  Hi ,I am a woman (56) suffering from rheumatoid arthritis my doctor has suggested regular & prolong use of a mdecine called Aviva.Could you please let me know whether this ......

Enbrel & Methotrexate and PPD test
  Is it recommended to still have a ppd skin test while on these meds? I know that they can cause a false neg, but are there any reactions or problems ......

Pregnancy & Humira
  I am a 35 year old woman & I take a 40 ml Humira Injection 2x a month. My husband and I are ready to start our family. I am ......

Risks for heart and lung problems on medications
  Currently i am on celebrex twice a day, methotrexate 15mg and prednisone 10mg a week.I recently stopped naproxen due gastritis.I was wondering, how high is the % of major problems ......

RA Medications
  Does any biological medications use for RA effect someone who has high blood pressure?     No. The only issue I can think of is that with the medications that ......

Possible side effect of Methotrexate
  My husband has RA. He was diagnosed in 1989. Initially he was on Placquinel. When that quit working the doctor put him on Methotrexate. I has been working real well. ......

Is TACE a good target for RA ??
  At present lot of work is being carried out on small molecule inhibitors of tnf alpha converting enzyme (TACE). As we all know, TACE is the enzyme which convert pro-TNF ......

RA Flares
  My RA is not under control yet. I am taking NSAID, Prednisone, and MTX. I know when I am going to flare. I flare every three months without fail. A ......

Starting Methotrexate
  I just started treatment with methotrexate. Since my first dose, I have been having terrible stomach pain, nausea and diarehha. Will this eventually subside, or this is part of the ......

Methotrexate and strange feeling in head
  Dear Doctor:I have been on methotrexate for 8 years 12.5 mg per week. The last couple of weeks I have had a very strange thing happen. About 5 hours after ......

Very Active RA
  My rheumatologist told me that my RA is still very active and he was concerned about my hands and feet due to the swelling. My next appointment is in August ......

Birth Control while on Methotrexate
  can i take birth control pills as a form of contraceptive if i am on methotrexate     Yes. Because of the risks of birth defects if you get pregnant ......

RA in fingers
  I have very active ra in my fingers. I type or write for 8 hours a day. So far the medications are not working very well. While I am typing ......

Remicaid therapy
  I am 37 years old. I have been diagnosed with gout and psoriatic arthritis. The doctor said I should start remicaid therapy. Will I have to take it always, is ......

Psoriatic arthritis and Remicade
  My brother has psoriatic arthritis ( and so do I). I am currently on Remicade and it is working great.My brother on the other hand is getting worse and worse. ......

Adding Enbrel
  I am taking Plaquenil,Methotrexate, Prednisone, and NSIAD for my RA and My doctor wants to add Enbrel. The meds that I am on now are not help very much. My ......

Plaquenil Side Effects
  I have RA and Plaquenil just got added to NSAID, MTX, and Prednisone. I am taking 400mg of Plaquenil, 20mg MTX, and 10mg Prednisone. I have only taken the Plaquenil ......

Can cyclophosphamide cause pain in joints?
  I have Lupus and am on monthly intravenous cyclophosphamide treatments and prednisone 30 mg daily to counteract vasculitis which is most obvious in my lower limbs, leg drop, pain, loss ......

Remicade and Pregnancy...is it safe?
  Hi, I'm 24, and have been on remicade for over a year now for Ulcerative Colitis. I'd like to know if it is safe to take remicade during your pregnancy. ......

Can cyclophosphamide cause pain in joints?
  I have Lupus and am on monthly intravenous cyclophosphamide treatments and prednisone 30 mg daily to counteract vasculitis which is most obvious in my lower limbs, leg drop, pain, loss ......

Edema of hands, legs, and feet while taking Methotrexate for RA
  Diagnosed with acute inflammatory Ra 2/06 - Being treated with methotrexate weekly and nsaids - pain and flare ups improved 60% - now have edema of hands legs and feet. ......

Should I start the Disease Modifying Agents?
  Hi,I am 39 years old anaesthesiologist.I have been experiencing pain in both knees for the last three years.There has never been a swelling.I remain fatigued throughout the day.I am also ......

Methotrexate and Celebrex
  My mother is currently on methotrexate (injections)and prednisone for a combination of RA and OA. Her doctor is trying to get her off prednisone and has put her on Celebrex ......

Humira for Severe RA
  My brother has severe rheumatoid arthitis.Some days he can not get out of bed or feed his self he is only 47 years old he was always a very health ......

Leukocytoclastic Vasculitis and Etanercept
  Dear Dr. Matsumoto,Is there an increased incidence, or severity, of leukocytoclastic (allergic) vasculitis with etanercept use? It looks like mine reappeared(confirmed by biopsy)and significantly increased in severity after having to ......

Taking Methotrexate and Enbrel together
  Right now I take 8 pills of MTX Friday night. I am about to start Enbrel. I am worried about any side effects. If I take them Friday then I ......

Adding Enbrel
  I have rheumatoid arthritis and taking Arthrotec, MTX, Plaquenil, and Prednisone. My doctor wants to start me on Enbrel. Can and is it normal to just add Enbrel to the ......

Rtuxan and Aava
  I am considering Rituxan to treating RA. I do not take Methotrexate but instead take Arava. Do you know of adverse effects of Rituxan in combination with Arava or the ......

Rituxan and Prednisone
  I have RA/Lupus/Sjogren's. A year ago I received Rituxan with good results. My symptoms are beginning to return. Recently, my husband died and I am more emotional than normal. I ......

Enbrel Injections
  I am going to start Enbrel in August. I was wondering who usualy shows me how to do the injection? A nurse, family doctor, my rheumatologist, or some type of ......

SureClick Enbrel
  Is the SureClick Enbrel prefilled pen in any way better/different (maybe cheaper?) than the regular Enbrel injection? When would you suggest that a patient uses the pen rather than the ......

Enbrel and Uveitis
  My 8 year old son has polyarticular ANA negative arthritis and started on Enbrel one year ago, in addition to methotrexate. He has recently developed uveitis that is proving difficult ......

Orencia or Rituxan
  I'm a 44 year old woman with a 20 year history of severe non-responsive RA. Having been through all of the other biologics my rheumatologist feels it is time to ......

Rheumatoid arthritis and infections
  I am on NSAID, Methotrexate, Prednisone and Plaquenil for my RA. But lately I have been getting alot of small infections. My big toe, a hangnail on my thumb and ......

Remicade cross placental barrier during pregnancy?
  August 19,2006Dear Dr. Motsumoto,I read your response to the Humera/pregnancy question in March and found it informative. Thank you for posting it.At age 29, My RA and CD had rendered ......

Side effects of Methotrexate
  Currently i take methotrexate but have noticed that i swell up when i take it for days after and by the end of the week i feel good on the ......

Enbrel
  I just had my first injection of Enbrel last night. So far there has not been any reactions from the drug. But about two hours after I got itchy in ......

Remicade
  If my husband has been on remicade (injections every two months over the past three years) are there risks for birth defects, and if so what typs of birth defects ......

Enbrel stopped working
  My husband has been taking Enbrel for 9 months. In the beginning it worked great and all the swelling and pain was gone. Now it has started to come back. ......

Enbrel, Metho, Humira
  I am 26 yrs old. I began taking 6 tablets of Metho and 50mg of Enbrel per wk since Jan. But around June to Aug I was getting my period ......

Methotrexate and getting pregnant
  My husband takes methotrexate for dermatomyositis. We have 1 child we conceived befoer he got sick. He has been on methotrexate for 2 years. How long does he have to ......

Humira and breast implants
  I have been taking humira for psoriatic arthritis for a couple of years now. I am young and will be on the medication for many years. I am considering having ......

Enbrel eye problems
  I am 23 and have had ra for 20 years i have the condition called stilis this year i got myo carditos very badly and nearly died i have been on ......

How safe is the flu shot while on Remicade?
  I have been on remicade for a year.Is it safe to get the flu shot this season? Also what do you think about foot surgery, when the inflamation and pain ......

Side Effects of Long Term Methrotrazate
  I have heard there can be some kind of lung side affect of long term methrotraze. Can you tell me anything about this. I have had a long term cough ......

Re: Methotrexate
  Sinse I started taking this medicine 11 months ago, I have being gaining weight and my stomack is getting big. After meals my stomach gets so big and relaxed as ......

Enbrel before colonoscopy
  Can you take regular shot of Enbrel on the same week of colonoscopy?     Enbrel does not need to be held. However, I suppose in those who want to ......

Humira and Skin Cancer risk
  Dr., do you think there is a greater risk of getting skin cancer if on the drug Humira? I have been on Enbrel, Remicade and now Humira for the last ......

Live vaccinations in RA patients
  I am pharmacy student on my clinical rotation. I recently had a doctor ask me if he could give the new shingles vaccine, Zostavax to a patient of his that ......

Pregnancy and Enbrel
  My daughter is thirty years old and is taking Enbrel. When she goes off of it to try and get pregnant. When she goes off of the medicine and hopefully ......

safely transporting biologic drugs
  I have found that when I am delivered my Humira, the drug is destroyed some times when the weather is either very hot or very cold, it just doesnt work ......

Can Methorexate cause gastritis or aggravate it?
  I have been on methorexate for about 2 yrs. for Takayasus.Was having stomach problems and was switched to injections (15mg). Have been off 2 mos. of steroids and just on ......

New medication
  What is this RA med I have heard about Ariva or Aviva?     Arava or leflunomide is not new. It has been approved for RA since 1998 and was ......

RA and MS
  I have RA and MS my question is do I have to decide between which disease to let be in control? If one is being treated , I have to ......

Enbrel and susceptability to flat warts.
  I have been using Enbrel for five years and have been bothered by flat warts the last six months or longer. My skin doctor has tried two methods of getting ......

Any alternatives for Prednisone
  Currently I have been on prednisone for a year now. I was doing ok at 7mg but not as good as 10. They brought me down to 5mg a day ......

Rash from Enbrel
  In Nov. 2006, I changed from using the 2 25Mg. kits weekly to the 50 mg. autoinjector weekly. I have noticed a significant increase in a rash and isolated bumpy, ......

Pregnant and was on Methotrexate
  Hi, I'm 6 wks pregnant and was taking mtx I'm pretty bad at taking my medication yet I know I did take it about 1 week before my last menstrual ......

Enbrel and strange pain
  My mother and I have had training in the injection of Enbrel so she can injected in the my arms when the time comes. Tonight she injected into my right ......

Exposure to Vaccinations
  I have RA/OA and have been on MTX and Enbrel for two + years. My white blood count tends to run low. Is there a problem with being around babies ......

Help for RA patients with no money
  I have a friend that is in very bad shape because his insurance co. refuses to pay for his medication of Enbrel. He does not make enough money to pay ......

Use of TNF's with CellCept
  I was recently diagnosed with spondyloarthritis and I also have myasthenia gravis which has been stable with CellCept and prednisone. The arthritis is not responding despite the doses of prednisone, ......

Can MTX be causing my dry cough?
  Back in Dec. 2006 I was diagnosed with an upper respitory infection and sinusitis.  I was tteated with antibiotics, Mucinex DM, and Hycotuss with Codiene clear cough syrup i got rid ......

Concerns about Arava
  I have been taking this drug for about 4 months now. I am having side effects that i didn't have before. My other meds (celebrex, prednisone) i have been on ......