Minocycline Trials

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<P>Why do you guys ignore the NIH study that proved in a placebo controlled trial minocycline was far more effective than placebo for RA?&nbsp; There is also a correlation w RA and an animal model with the microbe mycoplasma.&nbsp; </P>
<P>Dont patients have a right to know this? On your page the reasearch is funded by drug companies, could that be why?</P></TD></TR>
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<TD vAlign=top width=520>This forum has acknowledged on numerous occasions that minocycline has been extensively studied in human RA and has a modest benefit in the clinical trials.&nbsp; &nbsp; However,&nbsp;minocycline is not as effective as the newer biologic agents&nbsp;and is overall disappointing when used in our regular patients.&nbsp; The NIH did a large study in early human RA looking for a microbe that might cause RA using biopsies and cultures and PCR.&nbsp; The study failed to show a link with mycoplama or any other infection.&nbsp; Animal models do not replicate human RA.&nbsp;
<P>We also acknowledge&nbsp;that pharmaceutical companies help to fund this site and we work hard to maintain editorial independence.&nbsp; All funds are unrestricted and there is absolutely no input from the companies as to topic or content.&nbsp; We&nbsp;wish that there were other means to support our site so any contributions are welcome.</P></TD></TR></TBODY></TABLE>

Last update: 10:10 AM Monday, July 16, 2007

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