Remicade and Toxicity

Question  I have Ankylosing Spondalitis and have had 8 Remicaid infusions so far, at 8 week intervals.
The first 6 treatments left me feeling fantastic within a day of the treatment.
The last two infusions however, have left me feeling exhausted and nauseated for 5 days before returning to normal.
Could this be a sign of toxicity associated with Remicaid? What are the symptoms of toxicity?
 
Answer  Increased infusion reactions can be a sign of Remicade toxicity or to be more specific, a sign that your body may have developed antibodies against Remicade. However, it is somewhat unusual for the reactions to last 5 days. The usual complaint are flushing or rigors during the infusion and occasionally fatigue or malaise lasting a day or two. However, if no other explanation can be found for your symptoms, you may have to attribute it to Remicade.

Last update: 11:58 AM Friday, March 30, 2007

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Author:

Alan Matsumoto, M.D.

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